A modern approach to not only epidural space identification and confirmation but checking and confirming catheter placement in real time.

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Instant Epidural Catheter Verification with CompuWave™ Displaying the Pulsatile Waveform Found in the Epidural Space

A new, modern technique for checking your catheter placement in real time.

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Objectively Identify the Epidural Space with a 99% Success Rate on the First Attempt

A new, modern technique for objective identification and confirmation of the epidural space in real time for all your patients.

Since 1921

The Conventional Approach

Until recently, the identification of the epidural space has been based on the subjective perception of a “loss of resistance (LOR)”, when inserting an epidural needle to identify the epidural space.

  • Subjective tactile feel only - Requires subjective loss of resistance to air or saline
  • Sensitive but not specific - Detects pressure differences by loss of resistance, but is unable to differentiate between intermuscular planes, cysts, ligaments and the epidural space
  • Studies show it takes up to 90 epidural procedures to reach basic clinical competency

The New Standard

The CompuFlo® Epidural Instrument Uses DPS Dynamic Pressure Sensing Technology® System 1-4

  • Subjective tactile feel + objective DPS - differentiates between true loss and false loss of resistance
  • 25% reduction in procedure time for labor and delivery epidurals
  • Clinicians can successfully perform epidural procedures with fewer attempts
  • Detects subtle pressure changes 4 times a second, making it extremely responsive to minor pressure changes
  • Precisely controls the flow rate of fluid with real-time feedback, based on exit pressure at the needle tip
  • Compared to the traditional LOR technique, real-time pressure sensing technology costs about $504 dollars less per hospital stay on average
  • The CompuWaveTM display shows the pulsatile waveform found in the epidural space, again confirming needle and catheter placement

1 Ferrari M, Cagidiaco MC, Vichi A, Goracci C. Efficacy of the Computer-Controlled Injection System STATM, the Ligmaject, and the Dental Syringe for Intraligamentary Anesthesia in Restorative Patients. International Dentistry SA. 2008;11:4–12.

2 Jing Q, Wan K, Wang XJ, Ma L. Effectiveness and Safety of Computer-Controlled Periodontal Ligament Injection System in Endodontic Access to the Mandibular Posterior Teeth. Chin Med Sci J. 2014 Mar 31;29(1):23-7.

3 Kämmerer PW1, Schiegnitz E, von Haussen T, Shabazfar N, Kämmerer P, Willershausen B, Al-Nawas B, Daubländer M. Clinical Efficacy of a Computerised Device (STATM) and a Pressure Syringe (VarioJect INTRATM) for Intraligamentary Anaesthesia. Eur J Dent Educ. 2014 Mar 20.

4 Rovnat Babazade; Yu-li Lin; Hsu, En Shuo; Guillermo Hidalgo; Giorgio Capogna; Massimo Micaglio; Rakesh Vadhera; Ralf Gebhard. Cost Effectiveness Analysis of Two Labor Epidural Analgesia Techniques; Real-Time Pressure Sensing Technology and Traditional Technique. 45th Annual Regional Anesthesiology and Acute Pain Medicine Meeting; San Francisco, CA 2020.

Market Snapshot

Milestone Scientific, Inc.


NYSE American: MLSS


Market Cap


Day Range

52 WK Range